WHO guidelines on fluid resuscitation in children: missing the FEAST data
نویسندگان
چکیده
Sarah Kiguli consultant paediatrician , Samuel O Akech research fellow , George Mtove research fellow , Robert O Opoka consultant paediatrician , Charles Engoru consultant paediatrician , Peter Olupot-Olupot consultant paediatrician , Richard Nyeko consultant paediatrician , Jennifer Evans consultant paediatrician , Jane Crawley consultant paediatrician , Natalie Prevatt research fellow , Hugh Reyburn senior lecturer in clinical epidemiology , Michael Levin consultant paediatrician , Elizabeth C George statistician , Annabelle South policy, communications and research impact coordinator , Abdel G Babiker statistician , Diana M Gibb professor of epidemiology , Kathryn Maitland professor of tropical paediatric infectious disease 9
منابع مشابه
Causes of death after fluid bolus resuscitation: new insights from FEAST
The Fluid Expansion as Supportive Therapy (FEAST study) was an extremely well conducted study that gave unexpected results. The investigators had reported that febrile children with impaired perfusion treated in low-income countries without access to intensive care are more likely to die if they receive bolus resuscitation with albumin or saline compared with no bolus resuscitation at all. In a...
متن کاملRestrictive versus Liberal Fluid Resuscitation in Children with Dengue Shock Syndrome: the differences in Clinical Outcomes and Hemodynamic Parameters
Background: Fluid resuscitation is the mainstay of treatment to counteract massive plasma leakage in dengue shock syndrome. We aimed to determine the differences in clinical outcomes and hemodynamic parameters of children with dengue shock syndrome post restrictive and liberal fluid resuscitation. Materials and Methods: A retrospective observational study of pediatric patients who were betwee...
متن کاملMortality after Fluid Bolus in Children with Shock Due to Sepsis or Severe Infection: A Systematic Review and Meta-Analysis
INTRODUCTION Sepsis is one of the leading causes of childhood mortality, yet controversy surrounds the current treatment approach. We conducted a systematic review to assess the evidence base for fluid resuscitation in the treatment of children with shock due to sepsis or severe infection. METHODS We searched 3 databases for randomized trials, quasi-randomized trials, and controlled before-af...
متن کاملMortality and Other Outcomes in Relation to First Hour Fluid Resuscitation Rate: A Systematic Review.
OBJECTIVE To determine the effect of different regimen of first hour fluid administration rates on mortality and severe consequences of impaired circulation in 2 to 60 months old children with impaired circulation. DESIGN Systematic review of randomized controlled trials. DATA SOURCES Various databases including PubMed, Cochrane Library and EMBASE were searched. RESULTS We found only two ...
متن کاملAnaemia and blood transfusion in African children presenting to hospital with severe febrile illness
BACKGROUND Severe anaemia in children is a leading cause of hospital admission and a major cause of mortality in sub-Saharan Africa, yet there are limited published data on blood transfusion in this vulnerable group. METHODS We present data from a large controlled trial of fluid resuscitation (Fluid Expansion As Supportive Therapy (FEAST) trial) on the prevalence, clinical features, and trans...
متن کامل